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Pennsylvania's native reptile and amphibian species include salamanders, snakes, frogs, toads, turtles and lizards. The Pennsylvania Fish and Boat Commission has jurisdiction over reptiles and amphibians and works with partners to ensure that reptiles and amphibians remain protected in the Commonwealth.

The Pennsylvania Amphibian and Reptile Survey (PARS) helps determine the distribution and status of all reptiles and amphibians throughout Pennsylvania. The PFBC has the authority to protect threatened and endangered species.

The status of the Timber Rattlesnake was one of the first reptile and amphibian issues addressed by the Commission in 1974. Timber Rattlesnake Conservation has remained a constant topic of discussion, controversy and regulatory action within the Commission. The PFBC also does extensive work to monitor the Wood Turtle.